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≥99% Purity · HPLC verified

Research Use Only

NAD+

What is NAD+? NAD+ (β-Nicotinamide Adenine Dinucleotide) is an endogenous dinucleotide coenzyme central to cellular redox reactions. It serves as a substrate for sirtuins (NAD+-dependent deacetylases) and PARP enzymes (poly-ADP-ribose polymerases). Studied in laboratory settings for its role in mito…
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≥99% Purity

HPLC verified

Lab tested

HPLC + MS

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CERTIFICATE OF ANALYSIS THIRD-PARTY VERIFIED BY HPLC & MASS SPECTROMETRY
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Identity

Compound Information Information Information

NAD+ Overview

Nicotinamide adenine dinucleotide (NAD⁺) is a naturally occurring coenzyme central to redox reactions, bioenergetic processes, and molecular signaling. In laboratory and preclinical models, NAD⁺ has been studied for its role in mitochondrial function, genomic pathway signaling, and regulation of molecular resilience. Research continues to explore its influence on sirtuin activation, oxidative stress response, and downstream signaling pathways
CAS Number
53-84-9
Molecular Formula
C21H27N7O14P2
Molecular Weight
663.43 g/mol
Composition
β-Nicotinamide adenine dinucleotide (oxidized form)
Half-Life
Variable; intracellular pool turnover ~7 hours
Source
Enzymatically synthesized
Purity
99.0% (HPLC verified)
Form
Lyophilized powder
Solubility
Highly soluble in water, bacteriostatic water

History

NAD⁺ was first identified in the early 20th century during research into fermentation and molecular respiration. Its structure and biochemical role were later clarified, establishing it as a key coenzyme in enzymatic and signaling reactions. In recent decades, research has expanded to its involvement in genomic pathway signaling, age-associated biology, and molecular survival pathways, with growing use as a research tool in models of bioenergetic dynamics and stress response.

NAD+ Structure

Stability Information

Long-term

−20°C

Lyophilized powder, sealed

Reconstituted

2–8°C

Up to 30 days when refrigerated

Shipping

Room temp

Stable in transit, lyophilized

Protection

Light · Moisture

Store sealed, away from light

Research Findings

NAD⁺ has been investigated in bioenergetic, molecular, and systemic models, with research highlighting its role in mitochondrial function, redox dynamics, and molecular remodeling processes. Studies have also examined its influence on oxidative stress, genomic pathway signaling, and overall molecular resilience in preclinical settings.

Key Areas of Research:

Bioenergetic
Mitochondrial function, redox dynamics
Molecular
Genomic signaling, oxidative stress, viability
Systemic
Signaling, resilience, pathway dynamics

Together, these findings suggest broad experimental potential for NAD⁺ in supporting molecular and systemic biology. By engaging core bioenergetic pathways and influencing remodeling and stress responses, NAD⁺ provides a versatile platform for research into redox dynamics, molecular signaling, and systemic resilience in laboratory settings.

Important Safety Information

All products are sold strictly for in-vitro research and laboratory use only. Not for human or veterinary consumption, ingestion, injection, inhalation, application to the skin, or any other clinical use. Not approved by the FDA for any therapeutic purpose. Intended exclusively for qualified researchers in a controlled laboratory environment. By purchasing, you acknowledge and agree to use this material in compliance with all applicable laws and your institutional protocols.